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产物型号:Mouse FGF-4 Protein
更新时间:2025-06-23
厂商性质:生产厂家
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产物英文名称 | Mouse FGF-4 Protein |
产物中文名称 | 重组小鼠成纤维细胞生长因子4(贵骋贵-4) |
别名 | HST-1, Transforming protein KS3, HBGF-4 |
标签 | 无标签 |
表达宿主 | 大肠杆菌 |
种属 | 小鼠 |
序列 | 氨基酸序列来源于:小鼠FGF4 (P11403) (Ser67-Leu202) 表达的蛋白片段。 |
活性 | Testing in Progress |
蛋白长度 | 重组人 MIF 由120个氨基酸组成,预测分子量为13.1 KD。 |
纯度 | > 95 % ,使用SDS-PAGE检测 |
特点&优势 | 通过尝础尝法测定,每微克蛋白里内毒素含量<0.1>0.1> |
产物形式 | 冻干粉,冻干缓冲液为无菌的20 mM Tris,50 mM NaCl,pH 8.0。 |
基因滨顿 | 5008 |
蛋白序列链接 | Fgf4 - Fibroblast growth factor 4 - Mus musculus (Mouse) | UniProtKB | UniProt |
使用中注意事项 | 开盖使用前,请先离心。本产物为冻干粉,推荐用该产物配套的Reconstitution Buffer进行复溶,且浓度不低于100 µg/mL。客户可根据后续的实验需求,进行进一步的稀释。 |
保存建议 | 本产物为冻干粉形式,建议:将冻干粉产物保存于-20℃以下的干燥环境中。本产物溶解之后,可在4℃保存2-7天,长期使用请置于-20℃以下。为长期保存,推荐添加载体蛋白(0.1% HSA或者BSA),并酌情分装保存,避免反复冻融。 |
运输条件 | 冰袋运输(蓝冰) |
警告 | 本文列出的产物仅供研究使用,不适用于人类或临床诊断。我们产物所推荐应用,不是建议使用我们的产物去违反任何或许可证。对于使用本产物可能发生的侵权或其他违规行为,我们不承担任何责任。 |
背景 | Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development. |
Fig.Mouse FGF-4 Protein